I think the landing page needs a redesign and I suspect that the heavy influence of hand drawn mindmaps will be a turn off for heavy business users. (It feels like you are being bombarded with a bunch of napkin scribble when you first go to the site. The software tools do serve a valuable communication purpose. They clean up scribble and turn it into something that can be communicated from one mind to the next.)

I see a lot of potential for improvement in Mapio in general, whether or not the Mapio team will find that potential and realize it is another story.